Marmo-AD: Afonso Silva, Stacey Rizzo and their team propose to establish the marmoset as the first primate-specific model to reveal the earliest cellular and molecular events of AD processes and allow charting AD progression from its inception.
DNA damage-induced inflammation and its brain-specific consequences: Karl Herrup and his team will test each cell type in the brain for its role in contributing to the chronic inflammation found in Alzheimer’s and Parkinson’s.
Hot Flashes and Brain Aging in Women: Rebecca Thurston and her team are examining whether hot flashes, night sweats and sleep problems, the major symptoms of menopause, are associated with declines in cognitive and brain health over time in women. Find out more about their work here.
Dr. Oscar Lopez discusses his research that shows when and how much amyloid builds up…
In JAMA Network Open, Tharick Pascoal and his team showed that mood changes in Alzheimer’s…
PITTSBURGH (KDKA) — A study by the University of Pittsburgh claims to have found an…
Having more hot flashes, especially night sweats, during the transition to menopause may be associated…
What do we really know about Alzheimer’s, and what are the most promising ways to…
Pitt neurobiologist Or Shemesh has been awarded a three-year, $400,000 NIH Trailblazer Award from the…
In Nature Medicine, Tharick Pascoal and his team show that astrocytes have an important role…
Jennifer Lingler leads a $2.1 million NIH-funded study on the psychological and social impact of…
Single-cell multiregion dissection of Alzheimer’s disease
Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals
Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimer’s disease model mice
CenTauR: Toward a universal scale and masks for standardizing tau imaging studies
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease
Preanalytical stability of plasma/serum brain-derived tau
Meta-analysis of age-related cognitive decline reveals a novel locus for the attention domain and implicates a COVID-19-related gene for global cognitive function
Meeting report of the annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer’s Disease research
Plasma phospho-tau in Alzheimer’s disease: towards diagnostic and therapeutic trial applications
Blood-brain barrier integrity impacts the use of plasma amyloid-β as a proxy of brain amyloid-β pathology
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials
Plasma biomarkers identify older adults at risk of Alzheimer’s disease and related dementias in a real-world population-based cohort
Carotid intima media thickness and white matter hyperintensity volume among midlife women
Discriminative accuracy of the A/T/N scheme to identify cognitive impairment due to Alzheimer’s disease
Single-cell multiregion dissection of Alzheimer’s disease
Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals
Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimer’s disease model mice
CenTauR: Toward a universal scale and masks for standardizing tau imaging studies
Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease
Preanalytical stability of plasma/serum brain-derived tau
Meta-analysis of age-related cognitive decline reveals a novel locus for the attention domain and implicates a COVID-19-related gene for global cognitive function
Meeting report of the annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer’s Disease research
Plasma phospho-tau in Alzheimer’s disease: towards diagnostic and therapeutic trial applications
Blood-brain barrier integrity impacts the use of plasma amyloid-β as a proxy of brain amyloid-β pathology
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials
Plasma biomarkers identify older adults at risk of Alzheimer’s disease and related dementias in a real-world population-based cohort
Carotid intima media thickness and white matter hyperintensity volume among midlife women
Discriminative accuracy of the A/T/N scheme to identify cognitive impairment due to Alzheimer’s disease