Pitt is building a molecular brain map to understand Alzheimer’s disease

By: Anastasia Gorelova

Less than a decade ago, when Dr. Hansruedi Mathys launched an ambitious project to create an annotated library of all the gene readouts stored within 100 individual brain cells, the task felt daunting.

Now, with technological advances, Mathys successfully mapped out such ‘transcriptomes’ from not just 100, but from 1.3 million brain cortex cells from 48 individuals with and without Alzheimer’s disease.Read More on UPMC

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